Honey bees play important roles in pollination for many crops and wild plants, but have been facing great threats posed by various pathogens and parasites.Among them, Varroa destructor, an obligate ectoparasite of honey bees, is considered the most damaging.Within the last century, V.destructor shifted from the original host, the Asian honey bee Ap
Clinical profile of patients having myocardial bridge on coronary angiography at tertiary care hospital in Rajasthan
Introduction: Myocardial bridge (MB) is usually defined as the segment of the coronary artery (epicardial) which passes intramurally.In the early days, it was not having any clinical importance, but later studies jilungin dreaming tea showed the presence of it in the left anterior descending (LAD) artery can be associated with myocardial infarction
Synergistic inhibition of MEK and reciprocal feedback networks for targeted intervention in malignancy
The RAS-RAF-MEK-ERK signaling pathway (MAPK signaling pathway) plays a significant role jordan 12 nubuck in multiple pathological behaviors and is most frequently dysregulated in more than 30% of human cancers.As key elements in this pathway, MEK1/2 play crucial roles in tumorigenesis and the inhibition of apoptosis, which makes their inhibition an
ISG15 counteracts Listeria monocytogenes infection
ISG15 is an interferon-stimulated, linear di-ubiquitin-like protein, with anti-viral activity.The role of ISG15 during bacterial infection remains elusive.We show that ISG15 expression in nonphagocytic cells is dramatically induced upon Listeria infection.Surprisingly this induction can be type I interferon independent and depends on the cytosolic
Food preference strategy of four sympatric rodents in a temperate forest in northeast China
Rodents are well known as both seed predators and dispersers of various plant species in forest ecosystems, and they play an important role in the regeneration of vegetation.Thus, the research on seed selection and vegetation regeneration by sympatric rodents is an interesting topic.To understand the characteristics of preferences of rodents for di